Brief Introduction

Synonyms--- Neem, Azadirachta indica, Melia azadirachta L. Antelaea azadirachta (L.) Adelb.

Azadirachtin

Chemical Name: dimethyl (2aR,3S,4S,R,S,7aS,8S,10R,10aS,10bR)- 10- (acetyloxy)- 3,5-dihydroxy- 4-[(1S,2S,6S,8S,9R,11S)- 2-hydroxy- 11-methyl- 5,7,10-trioxatetracyclo [6.3.1.0^2,6.0^9,11] dodec- 3-en- 9-yl]- 4-methyl- 8-{[(2E)- 2-methylbut- 2-enoyl]oxy}octahydro- 1H-furo[3',4':4,4a]naphtha [1,8-bc]furan- 5,10a(8H)-dicarboxylate
Molecular Formula: C₃₅H₄₄O₁₆

Mol. Wt.: 720.71 g/mol

Molecular Structure:

Azadirachta indica (Neem) is a tree in the mahogany family Meliaceae. It is one of two species in the genus Azadirachta, and is native to India, China, Burma, Bangladesh, Sri Lanka, Malaysia and Pakistan, growing in tropical and semi-tropical regions. Neem is a fast-growing tree that can reach a height of 15–20 m (about 50–65 feet).

The Indian scientists were the first scientist to bring the plant to the attention of phytopharmacologists. In 1942, while working at the Scientific and Industrial Research Laboratory at Delhi University, British India, he extracted three bitter compounds from neem oil, which he named nimbin, nimbinin, and nimbidin respectively. The seeds contain a complex secondary metabolite azadirachtin, and azadirachtol. The leaves and barks contain Alkaloids, Saponins, Tannins, Glycosides Combined anthraquinones, Anthraquinone derivatives, Terpenes, Flavonoids , Reducing sugars, Ketones, Pentoses, Monosaccharide, General Carbohydrates, and etc.

In India, the tree is variously known as "Sacred Tree," "Heal All," "Nature's Drugstore," "Village Pharmacy" and "Panacea for all diseases." Products made from neem tree have been used in India for over two millennia for their medicinal properties: Neem products have been observed to be anthelmintic, antifungal, antidiabetic, antibacterial, antiviral, contraceptive and sedative. Neem products are also used in selectively controlling pests in plants. It is considered a major component in Ayurvedic and Unani medicine and is particularly prescribed for skin disease.

All parts of the tree are said to have medicinal properties (seeds, leaves, flowers and bark) and are used for preparing many different medical preparations.

Part of the Neem tree can be used as a spermicide

Neem oil is used for preparing cosmetics (soap, neem shampoo - Sunsan herbal, balms and creams, for example Margo soap), and is useful for skin care such as acne treatment, and keeping skin elasticity. Neem oil has been found to be an effective mosquito repellent.

Neem derivatives neutralise nearly 500 pests worldwide, including insects, mites, ticks, and nematodes, by affecting their behaviour and physiology. Neem does not normally kill pests right away, rather it repels them and affects their growth. As neem products are cheap and non-toxic to higher animals and most beneficial insects, they are well-suited for pest control in rural areas.

Practitioners of traditional Indian medicine recommend that patients suffering from chicken pox sleep on neem leaves.

Neem gum is used as a bulking agent and for the preparation of special purpose food (for diabetics).

Aqueous extracts of neem leaves have demonstrated significant antidiabetic potential.

Extract of neem leaves is thought to be helpful as malaria prophylaxis despite the fact that no comprehensive clinical studies are yet available. In several cases, private initiatives in Senegal were successful in preventing malaria. However, major NGOs such as USAID are not supposed to use neem tree extracts unless the medical benefit has been proved with clinical studies.

Uses in pest and disease control: Neem is deemed very effective in the treatment of scabies, although only preliminary scientific proof, which still has to be corroborated, exists, and is recommended for those who are sensitive to permethrin, a known insecticide which might be an irritant. Also, the scabies mite has yet to become resistant to neem, so in persistent cases neem has been shown to be very effective. There is also anecdotal evidence of its effectiveness in treating infestations of head lice in human. The oil is also used in sprays against fleas for cats and dogs.

The Azadiractha Indica Extract used in dietary supplements is derived from the leaves/barks/fruits of the plant neem (Azadiractha Indica).

Benefits

• anthelmintic,

•antifungal,

•antidiabetic,

•antibacterial,

•antiviral,

•contraceptive

•sedative

Mechanism

Not available.

Safety

Azadiractha Indica is tonic, please consult the physicians when use it.

Dosage

•  Consult physicians for different condition specifics.

GNI’s Azadiractha Indica Features and Benefits:

Azadiractha Indica Extract is one of GNI's most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from  seeds.

•  Produced with pure water only

•  High purity

•  NO solvent - residual free

•  Pesticide-free

•  Brown-Yellow in appearance

•  High solubility in water

•  High anti-bacteria, and longer shelf life

Product Specifications:

15% Azadirachtin