Brief Introduction

Synonyms---

Phloridzin (Phlorhizin; Phlorizoside)

Chemical Name: Phloretin-2'-O-glucoside; 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside; 1-propanone, 1-[2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-; 1-[2,4-Dihydroxy-6-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-3-(4-hydroxy-phenyl)-propan-1-one

Cas Number: 60-81-1

Molecular Formula: C₂₁H₂₄O₁₀

Mol. Wt.: 436.42 g/mol

Molecular Structure:

The apple tree, species Malus domestica in the rose family Rosaceae is one of the most widely cultivated fruit trees. The apple forms a tree that is small and deciduous, reaching 3 to 12 metres (9.8 to 39 ft) tall, with a broad, often densely twiggy crown. The leaves are alternately arranged simple ovals 5 to 12 cm long and 3–6 centimetres (1.2–2.4 in) broad on a 2 to 5 centimetres (0.79 to 2.0 in) petiole with an acute tip, serrated margin and a slightly downy underside. Blossoms are produced in spring simultaneously with the budding of the leaves. The flowers are white with a pink tinge that gradually fades, five petaled, and 2.5 to 3.5 centimetres (0.98 to 1.4 in) in diameter. The fruit matures in autumn, and is typically 5 to 9 centimetres (2.0 to 3.5 in) diameter. The center of the fruit contains five carpels arranged in a five-point star, each carpel containing one to three seeds.

The tree originated in Central Asia, where its wild ancestor is still found today. There are more than 7,500 known cultivars of apples resulting in a range of desired characteristics. At least 55 million tons of apples were grown worldwide in 2005, with a value of about $10 billion. China produced about 35% of this total.

Phloridzin (Phlorhizin, Phlorizin) is a glucoside derived from the root bark of the apple, pear, cherry, etc. Phloridzin is glycosylated derivative from phloretin, which is an anti-oxidant agent.

The Apple Phloridzin Extracts are of the below listed properties and effects:

1)       Anti-tumor for the treatment result to the skin cancer

2)       Anti-diabetics

3)       Can obstruct the sebum cell that the glucose enters epidermis, reduce sebum to secrete

4)       The Face thing in the usage can repress the formation of the melanin, reduce thin and dark brownish green, the gray spot and color and luster of the freckle

5)       Scavenge the free radicals in the blood sugar, blood pressure, the protection heart and the clearance bodies of regulates

The Apple Root Bark Extract used in dietary supplements is derived from the root bark of the plant apple tree (Malus domestica).

Benefits

•Anti-diabetics

•Anti-cancer (Skin cancer)

• Anti-tumor

•Anti-oxidant

•Free radical scavenging Effects

Mechanism

Referring to the above information.

Safety

Apple Root Bark Extract is safe.

Dosage

•  The typical dose is 300-900mg per day (usually in 2-3 doses throughout the day).
•  Consult physicians for different condition specifics.

GNI’s Apple Root Bark Extract Features and Benefits:

Apple Root Bark Extract is one of GNI's most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from apple tree root bark (Malus domestica).

•  Produced with pure water only

•  High purity: over 98%

•  NO solvent - residual free

•  Pesticide-free

•  Bright Yellow in appearance

•  High solubility in water

•  High anti-bacteria, and longer shelf life

Product Specifications:

40%, 60%,  80%, 90%, 98%Phloridzin HPLC