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Changsha Jiekai Biological Products Co., Ltd.
Contact Phone:
86-0731-82287663
86-0731-82284663
Fax number:
86-0731-82284663
Zip Code: 410016
Address: Room 2505, Block A, East County Huacheng Plaza, No. 166, Section 1, Wanjiali Middle Road, Changsha City, Hunan Province

Products Name:

Garcinia Cambogia Fruit Extr


Garcinia Cambogia Fruit Extr
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  • Garcinia Cambogia Fruit Extr

Latin name:

Garcinia cambogia

Plant part used:

Fruit Rind

Specification:

50%, 60% HCA

Testing methods:

HPLC

CAS No:

6205-14-7

Main functions:

Anti-obesity


Classification:

G

Key words:

Consult

Describe


Brief Introduction

Synonyms---Garcinia gummi-gutta, Garcinia gummi-gutta (L.) N.Robson, Garcinia quaesita, Gambooge, Brindleberry, Brindall berry, Malabar tamarind, Kodumpuli (Malayalam/Kerala), or Goraka (Sri Lanka), HCA,

Hydroxycitric acid(Hydroxycitrate)

Chemical Name:1, 2-dihydroxypropane-1,2,3-tricarboxylic acid
Molecular Formula: C6H8O8

Mol. Wt.:208.12292

Molecular Structure:

jk

Garcinia cambogia(syn. G.gummi-gutta, G. quaesita) is a subtropical species of Garcinia native to Indonesia. It is grown for its fruit in Southeast Asia, and west and central Africa. It thrives in moist forests. The yellowish fruit is pumpkin-shaped.

In Indian traditional medicine, this species was prescribed for edema, delayed menstruation, constipation and intestinal parasites. It was also used for rheumatism and bowel complaints.

The extract and rind of Garcinia cambogia is a curry condiment in India. Extracts from this species are an ingredient in some herbal appetite suppressant and energy products, though there is no formal evidence to support its effectiveness. It is used in weight-loss supplements.

Hepatotoxicity (liver toxicity) from weight-loss supplements which contain extracts of Garcinia cambogia has been reported.

Hydroxycitric acid(HCA) is a derivative of citric acid that is found in a variety of tropical plants including Garcinia cambogia and Hibiscus subdariffa. Laboratory and animal studies of HCA have produced results that indicate a potential for modulation of lipid metabolism; consequently HCA is an ingredient in some weight loss products and dietary supplements. However, a clinical study has demonstrated that HCA has no effect in terms of weight loss or reduction of fat mass.

One isomer of HCA, known as (2S, 3R)-HCA, inhibits pancreatic alpha-amylase and intestinal alpha-glucosidase, leading to a reduction in carbohydrate metabolism in vitro. In a study in Zucker rats which are genetically predisposed to obesity, Garcinia cambogia extract containing HCA showed that high doses led to significant suppression of epididymal fat accumulation, but also caused potent testicular atrophy and toxicity. However, this study has been criticized because of possible contamination of the HCA used and various design flaws.

The Garcinia cambogia Extract used in dietary supplements is derived from the fruit rinds of the plant Garcinia cambogia.

Benefits

• Promote weight loss by suppressing appetite

• Treat edema,

Delayed menstruation, constipation and intestinal parasites.

Treat rheumatism and bowel complaints.

Mechanism

Specifically, hydroxycitric acid is a competitive inhibitor of adenosine triphosphate-citrate. In the cytosol, ATP citrate lyase catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (commonly referred to as acetyl CoA). Acetyl CoA is required for the synthesis of fatty acids, cholesterol and triglycerides.

Oxaloacetate may enter the gluconeogenic pathway, which can lead to the production of glucose and glycogen. Many researchers and experts assert that the putative antiobesity effect of hydroxycitric acid is due to suppression of fatty acid and fat synthesis. Additionally, hydroxycitric acid is believed to suppress food intake via an anorectic effect, which also supports the belief that HCA may assist in weight loss.

Studies suggest that garcinia cambogia may assist in weight loss for the following reasons:

·HCA appears to block the conversion of sugars and starches into fats, that this, HCA is believed to help inhibit fat production.

·HCA may suppress appetite by raising levels of certain brain chemicals such as serotonin, a key stimulator of appetite.

However, there is no concrete evidence that supports the conclusion that garcinia cambogia can in fact cause weight loss. However, in a study of 60 overweight participants who took the supplement for 2 months, HCA appeared to help participants lose weight when compared with other study participants who were given a placebo.

Safety

Garcinia Cambogia is safe, no serious side effects have been reported to date, but relying on this type of treatment alone, and avoiding conventional medical care, may have serious health consequences.

Dosage

• The typical dose is 250-1000mg per day (usually in 2-3 doses throughout the day).
• Consult physicians for different condition specifics.

GNI’s Garcinia cambogia Extract Features and Benefits:

Garcinia cambogia Extract is one of GNI's most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from Garcinia cambogia fruit rinds.

• Produced with pure water only

• High purity: over 60%

• NO solvent - residual free

• Pesticide-free

• Off-white in appearance

• High solubility in water

• High anti-bacteria, and longer shelf life

Product Specifications:

50%, 60% Hydroxycitric acid (HCA)

Immediately Consult